five

Accelerated Midlife Endocrine and Bioenergetic Brain Aging in APOE4 Female Mice

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE282066
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Age, female sex and APOE4 genotype are top Alzheimer’s risk factors. Using a translational perimenopause mouse model based on STRAW criteria, we investigated APOE genotype impact on female midlife endocrine aging. Hippocampal gene expression data of APOE3 and APOE4 female mice across different chronological and endocrinological aging groups.
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2025-07-30
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