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Identification of novel human Wnt target genes using adult endodermal tissue-derived organoids

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE167115
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WNT and/or Rspondin was withdrawn from the medium and Wnt pathway inhibitors IWP2 and DKK1 were added to the growth medium of human stomach, liver, pancreas, small intestinal and colon organoids and RNA was harvested at time points 0h, 6h and 24h to identify Wnt regulated genes. RNA transcriptomics analysis upon WNT pathway inhibition in five different human tissue derived organoid lines of time point 0h, 6h, 24h. N=3
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2021-02-22
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