HIV- Modulated Proteins Associated with Lipid Metabolism

The three downregulated proteins are marked with (*). All other (n = 8) proteins were either expressed exclusively in HIV-infected cells or were upregulated compared to those detected in the uninfected cells. Protein names, abbreviations, locations and accession numbers are according to SwissProt. Putative functions and significance scores in relation to lipid metabolism were calculated by Fisher Exact Test using software from Ingenuity Systems Inc. A p-value of <0.05 represents a statistically significant non-random association of a specific protein with a lipid-related function/s in the Global Functional Analysis