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X-ray structure of human PPAR delta ligand binding domain in complex with a synthetic agonist 16a

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Protein Data Bank Japan2026-07-08 更新2026-08-24 收录
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X-ray structure of human PPAR delta ligand binding domain in complex with a synthetic agonist 16a Descriptor: 6-[2-[[2-[4-(trifluoromethyloxy)phenyl]benzimidazol-1-yl]methyl]phenoxy]hexanoic acid, Peroxisome proliferator-activated receptor delta Authors: Dai, L, Sun, H, Feng, Z. Deposit date: 2024-05-27 Release date: 2025-12-24 Last modified: 2026-07-08 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Design, Synthesis, and Biological Evaluation of Arylimidazole Derivatives as Potent PPAR delta Agonists for the Treatment of Renal Fibrosis. J.Med.Chem., 69, 2026

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2024-05-27
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