Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SGC0946
收藏Protein Data Bank Japan2023-09-27 更新2026-04-04 收录
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Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SGC0946 Descriptor: 5-bromo-7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Transcription factor ETV6,Guanine-N7 methyltransferase nsp14 chimera, ZINC ION Authors: Kottur, J, Aggarwal, A.K. Deposit date: 2023-01-07 Release date: 2023-07-26 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.57 Å) Cite: Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals. Plos Pathog., 19, 2023
创建时间:
2023-01-07



