five

Gene expression profiles in normal and Otx2-/- early gastrulating mouse embryos

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE683
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We compared gene expression profiles in wild-type and Otx2(-/-) 6.5 days postcoitum embryos by using a serial analysis of gene expression assay adapted to microdissected structures. Among a broader list, the study of six genes found to be differentially expressed allows defining a role for Otx2 in the orchestration of cell movements leading to the adequate organization of the embryo before gastrulation. Keywords: other
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2012-03-02
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