Effects of dipeptidyl peptidase IV (DPP4) inhibition via BI 14332 to relative numbers of CD4⁺ and CD8⁺ T-lymphocytes (LSmean ± SE).

aWith first occurrence of serum β-hydroxybutyrate ≥ 1.2 mM cows were treated with BI 14332 (HC-BI) or stayed untreated as control group (HC-Con). BI 14332 was applied once a day over a period of 7 days (0.3 mg/kg body weight). Subclinical ketosis was diagnosed on day +3 (1 cow), day +7 (8 cows) or on day +10 (3 cows) after calving. Significant values (P ≤ 0.05) and trends (P ≤ 0.1) are shown in bold. LSmeans with different superscripts (a-b) within the same group are significantly different. Effects of dipeptidyl peptidase IV (DPP4) inhibition via BI 14332 to relative numbers of CD4+ and CD8+ T-lymphocytes (LSmean ± SE).