Preclinical characterization of AZD3839, a novel clinical candidate BACE1 inhibitor for the treatment of Alzheimer Disease
收藏Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/4b05
下载链接
链接失效反馈官方服务：
资源简介：
Preclinical characterization of AZD3839, a novel clinical candidate BACE1 inhibitor for the treatment of Alzheimer Disease Descriptor: (1S)-1-[2-(difluoromethyl)pyridin-4-yl]-4-fluoro-1-(3-pyrimidin-5-ylphenyl)-1H-isoindol-3-amine, ACETATE ION, BETA-SECRETASE 1, ... Authors: Jeppsson, F, Eketjall, S, Janson, J, Karlstrom, S, Gustavsson, S, Olsson, L.L, Radesater, A.C, Ploeger, B, Cebers, G, Kolmodin, K, Swahn, B.M, von Berg, S, Bueters, T, Falting, J. Deposit date: 2012-06-28 Release date: 2012-10-17 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Discovery of AZD3839, a potent and selective BACE1 inhibitor clinical candidate for the treatment of Alzheimer disease. J. Biol. Chem., 287, 2012
创建时间：
2012-06-28
