Nog

ENCODES a protein that exhibits protein-containing complex binding; cytokine binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN cellular response to BMP stimulus; cellular response to hypoxia; forebrain development; PARTICIPATES IN Bone morphogenetic proteins signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; ASSOCIATED WITH acute kidney tubular necrosis; Pulmonary Hypertension, Hypoxia-Induced ; type 2 diabetes mellitus; FOUND IN axon; extracellular space; protein-containing complex; INTERACTS WITH (20S)-ginsenoside Rg3; 17beta-estradiol; 6-propyl-2-thiouracil

编码一种具有蛋白质复合物结合特性、细胞因子结合（同源）；蛋白质同源二聚化活性（同源）；参与细胞对BMP刺激的响应；细胞对低氧的响应；前脑发育；参与骨形态发生蛋白信号通路；转化生长因子-β超家族介导的信号通路；与急性肾小管坏死、肺高血压、低氧诱导相关；2型糖尿病；存在于轴突、细胞外空间、蛋白质复合物中；与（20S）人参皂苷Rg3、17β-雌二醇、6-丙基-2-硫尿嘧啶相互作用。