Univariate analysis of clinico-pathological parameters influencing tumour-specific survival in the group of gradea 1 and 2 breast tumours.

aAccording to Bloom and Richardson, as modified by Elston and Ellis [32].bLog-rank test at the two-sided significance level of 0.05.cMedian immunoreactive score (IRS) according to Remmele and Stegner [30] was used as cut-off: AGR3 low (IRS 0–4), AGR3 high (IRS 6–12).dAccording to TNM classification by Sobin and Wittekind [58].eImmunoreactive score (IRS) according to Remmele and Stegner [30].fOverexpression of the ERBB2 gene (Her-2/neu) was diagnosed analogously to the threshold of the DAKO-Score system based on IHC assay. Significant P-values are marked in bold face.Univariate analysis of clinico-pathological parameters influencing tumour-specific survival in the group of gradea 1 and 2 breast tumours.