Demographic and clinical characteristics of MS patients, healthy controls and non-inflammatory neurological controls included in the studies.

Values for age, MS disease duration, EDSS and EDSS change are medians with interquartile ranges in brackets. EDSS change represents the change in EDSS the two previous years prior to blood sampling. Abbreviations: CSF = cerebrospinal fluid; EDSS = expanded disability status scale; HC = healthy control; MS = multiple sclerosis; NIND = non-inflammatory neurological disease; RRMS = relapsing-remitting multiple sclerosis; SPMS = secondary progressive multiple sclerosis; PPMS = primary progressive multiple sclerosis.