Transcriptome of zebrafish (Danio rerio)

Zebrafish (Danio rerio) have been used as a model organism to study innate immune system and hostpathogen interactions. Until now, the information related to the immune system against A. hydrophila of zebrafish and the treatment by probiotics is incomplete. To increase knowledge of the molecular mechanisms of the host defense against A. hydrophila and provide evidence that antibiotics can replace by probiotics, we conducted transcriptome analysis of spleen in zebrafish 48 h post-infection and treatment by Lactococcus lactis after 4h post-infection via sequencing.