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Aedes CpA-Dcr2 and CpA-R2d2 transgenic mosquitoes midguts RNA-seq data at 24h PBM

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP375249
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The innate immune system of the mosquitoes defends against a variety of pathogens and the conserved siRNA pathway plays a central role in the control of viral infections. We have generated transgenic Aedes mosquitoes overexpressing Dicer2 (Dcr2) or R2d2 under the blood-meal inducible midgut specific promoter carboxypeptidase A (CpA) promoter. Through RNA-seq we have compared the mRNA abundance in the CpA-Dcr2 or CpA-R2d2 midguts compared to the wild type (WT) midguts at 24h post blood meal (PBM).
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2022-05-19
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