A precisely positioned MED12 activation helix stimulates CDK8 kinase activity
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https://www.omicsdi.org/dataset/pride/PXD015394
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资源简介：
Chemical cross-linking coupled to mass spectrometry was used to study binary and ternary complexes involving cyclin-dependent kinase 8 (CDK8), cyclin-C, and subunit 12 of the Mediator complex (MED12). Cross-linking was performed using different cross-linking chemistries: (1) disuccinimidyl suberate (DSS); (2) a combination of pimelic acid dihydrazide (PDH) and the coupling reagent, DMTMM.
创建时间：
2020-01-16
