Keloid Transcriptome

Eevaluation of intra- and inter-keloid fibroblast heterogeneity by analyzing their gene expression using transcriptomic analysis Comparison between nodular or extensive keloids, each of them being separated into four regions: on one side center versus periphery, on the other side papillar (or superficial) and reticular (or deep) regions . This leads to four fibroblast subtypes: central papillary (CP), central reticular (CR), peripheral papillary (PP) and peripheral reticular (PR) all compared to control skin from superficial/papillary (Pap) or deep/reticular (Ret) dermis