Nlrp6 is expressed by T cells, but whether Nlrp6 influences the transcriptom of T cells is not known Methods: Equal numbers of Wild Type and Nlrp6-/- CD4 T cells were adoptively transfered in RAG-/- h

NIAID Data Ecosystem40

Expression data of CNS T cells during EAE

自身免疫性脑脊髓炎

T细胞转录组

In the absence of NR4A2 in T cells mice do not develop early acute EAE, but only a late chronic disease. We examined the mechanism by which NR4A2 can control the pathogencity of T cells in CNS autoim

NIAID Data Ecosystem30

Understanding how IL-2 cytokine synergizes with PD-1 directed immunotherapy during chronic viral infection [RNA-seq]

免疫疗法机制

T细胞转录组

This work aimed to understand how different IL2 varients Overall design: Mice infected with LCMV-clone13 were treated with various immunotherapies. Antigen specific CD8 T-cells were sorted from mice 2

NIAID Data Ecosystem40

Data_Sheet_4_An Inflammatory Loop Between Spleen-Derived Myeloid Cells and CD4+ T Cells Leads to Accumulation of Long-Lived Plasma Cells That Exacerbates Lupus Autoimmunity.PDF

皮肤红斑狼疮免疫学

浆细胞-免疫细胞环路

Splenic long-lived plasma cells are abnormally numerous and deleterious in systemic autoimmune diseases, yet how they accumulate remains poorly understood. We demonstrate here that a pathological role

NIAID Data Ecosystem30

Homo sapiens Transcriptome or Gene expression. Homo sapiens

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