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Low-grade glioma microglia. Mus musculus

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA275388
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To examine the effect of Nf1 inactivation in astrocytes on normal microglia in the optic nerve, microglia from Nf1 flox/flox (FF) and Nf1 flox/flox; GFAP-Cre (FFC) were flow sorted. High throughput RNA-seq was employed to compare the expression profiles, and upregulated genes in microglia supportive to Nf1 deficient astrocytes were verified. Overall design: Microglia from mice lacking Nf1 in astrocytes were flow sorted. Upregulated genes were verified and further examined.
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2015-02-11
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