Probability of the spectrum of rpoB mutations in the INH-resistant mutant and the wildtype parent being identical.

The probability of hypothesis h0b (the spectrum of rpoB-mutations of the INH-resistant mutant is not different than that of the wildtype parent) determined by X2 for all INH-resistant strains for both methods. For all of the tested strains the statistical power of the X2 test was reduced due to one or more mutations occurring less than five times. NA: not available, mutants were not obtained for these strains.*: since both 2001-1669 and 2001-1670 are resistant to INH (via katG-S315T), the spectrum was compared to the only susceptible LAM strain, 9900098. Bold: pa