Crystal structure of c-Met-D1228N in complex with KIN-7615
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Crystal structure of c-Met-D1228N in complex with KIN-7615 Descriptor: Hepatocyte growth factor receptor, N-(3,5-difluoro-4-{[6-(2-hydroxyethoxy)-7-methoxyquinolin-4-yl]oxy}phenyl)-4-methoxypyridine-3-carboxamide Authors: Ouyang, X, Kania, R, Cox, J. Deposit date: 2024-01-02 Release date: 2025-04-02 Last modified: 2025-06-25 Method: X-RAY DIFFRACTION (3.11 Å) Cite: Discovery of KIN-8741, a Highly Selective Type IIb c-Met Kinase Inhibitor with Broad Mutation Coverage and Quality Drug-Like Properties for the Treatment of Cancer. J.Med.Chem., 68, 2025
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2024-01-02
