Transcriptome analysis in shNull and shSETD8 medulloblastoma cells. Transcriptome analysis in shNull and shSETD8 medulloblastoma cells

The goal of this study was to determine the effect on gene transcription profiles in medulloblastoma cells that were depeleted of the epigenomic modifier SETD8 vs control. Overall design: RNA-seq was performed using the illumina HiSEQ 4000 HT for 1x50 sequencing. High quality base calls at 95% ≥ Q30 were obtained with 53M-69M single reads. Statistical analysis of count data was performed with DESeq2 R package.