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Trifluoromethanesulfonyl Hypervalent Iodonium Ylide for Copper-Catalyzed Trifluoromethylthiolation of Enamines, Indoles, and β‑Keto Esters

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Figshare2016-02-19 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Trifluoromethanesulfonyl_Hypervalent_Iodonium_Ylide_for_Copper_Catalyzed_Trifluoromethylthiolation_of_Enamines_Indoles_and_Keto_Esters/2404009
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A novel electrophilic-type trifluoromethylthiolation reagent, a trifluoromethanesulfonyl hypervalent iodonium ylide, was designed and reacted well with various nucleophiles to afford the desired CF3S-substituted products. In situ reduction of the trifluoromethanesulfonyl group to give the trifluoromethylthio group, which is the key step in this process, was realized in the presence of copper­(I) chloride.
创建时间:
2016-02-19
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