TARGETED MODIFICATION OF MALATE DEHYDROGENASE
收藏国家林业和草原科学数据中心2023-02-12 更新2024-03-07 收录
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资源简介：
The present invention relates to a tomato plant cell in which the sequence of an endogenous mitochondrial malate dehydrogenase (mMDH) gene is modified by a nuclease that binds to a target sequence within any of SEQ ID Nos:3-10 and cleaves the mMDH gene within or between SEQ ID NO:3 and 4， within or between SEQ ID NO:5 and 6， within or between SEQ ID NO:7 and 8 or within or between SEQ ID NO:9 and 10， such that activity of an expressed mMDH protein is reduced as compared to an unmodified tomato plant cell， wherein the tomato plant cell is not part of a whole tomato plant. Disclosed herein are methods and compositions for targeted modification of one or more endogenous plant malate dehydrogenase genes.
提供机构：
国家林业和草原科学数据中心
创建时间：
2023-02-12
