Transcriptome analysis of allospecific CD8 T cells in murine pregnancy or graft rejection. Transcriptome analysis of allospecific CD8 T cells in murine pregnancy or graft rejection

RNAseq analysis of CD8 T cells after pregnancy-induced tolerance/hypofunction. The goal of this experiment was to compare the transcriptional effect of pregnancy on naive vs. memory fetus-specific CD8 T cells. We also included naive and skin-sensitized CD8 T cells (without pregnancy) as controls. Overall design: T cells were sorted by flow cytometry and RNA-seq was performed.