CjPCA
收藏国家生物信息中心2025-10-11 更新2025-03-15 收录
下载链接：
https://cjpca.ninds.nih.gov
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资源简介：
To understand the cellular composition and region-specific specialization of white matter - a disease-relevant, glia-rich tissue highly expanded in primates relative to rodents - we profiled transcriptomes of ~500,000 nuclei from 19 tissue types of the central nervous system of healthy common marmoset and mapped 87 subclusters spatially onto a 3D MRI atlas. We performed cross-species comparison, explored regulatory pathways, modeled regional intercellular communication, and surveyed cellular determinants of neurological disorders. Here, we analyze this resource and find strong spatial segregation of microglia, oligodendrocyte progenitor cells, and astrocytes.
提供机构：
National Institutes of Health
创建时间：
2023-08-23
