Different parameters of maximal vasodilation induced by acetylcholine iontophoresis (Peak ACh) studied in protocol 1 and protocol 2.

Cutaneous vascular conductance (CVC) is calculated as the laser signal value divided by the mean arterial pressure when the measurement is performed. When multiple current applications were performed, the number after each above parameters ranges from 1 to 4 corresponds to the number of current applications. For e.g., Peak 2 ACh(CVC) corresponds to the maximal vasodilation obtained after the second current application and is expressed in CVC. min means minutes.