Crystal structure of CYP3A4 ligated to pyridine-substituted desoxyritonavir
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Crystal structure of CYP3A4 ligated to pyridine-substituted desoxyritonavir Descriptor: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, pyridin-3-ylmethyl [(2R,5S)-5-{[N-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-D-valyl]amino}-1,6-diphenylhexan-2-yl]carbamate Authors: Sevrioukova, I.F, Poulos, T.L. Deposit date: 2012-11-27 Release date: 2013-04-24 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Pyridine-Substituted Desoxyritonavir Is a More Potent Inhibitor of Cytochrome P450 3A4 than Ritonavir. J.Med.Chem., 56, 2013
创建时间：
2012-11-27
