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Shotgun Metagenomics Fecal Microbiome Dysbiosis in Parkinsons Disease

NIAID Data Ecosystem2026-03-11 收录

帕金森病微生物组

肠道菌群失调

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP257563 数据链接链接失效反馈

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资源简介：

Shotgun Metagenomics raw sequences. Fecal microbiome data in PD subjects and healthy control subjects.

应用场景：

创建时间：

2020-04-20

肠道菌群失调

结肠炎机制

we found that deficiency of the E3 ligase Itch, which leads to spontaneous colitis and rectal prolapse, is associated with alteration of the gut microbiota. 16S rRNA sequencing showed expansion of col

NIAID Data Ecosystem80

NOD2 transmissible microbiota predispose WT mice to inflammation

肠道菌群失调

免疫转录组

Instability in the composition of gut bacterial communities, referred as dysbiosis, has been associated with important human intestinal disorders such as Crohn’s disease and colorectal cancer. Our dat

NIAID Data Ecosystem70

Porphyromonas gingivalis-mediated gut microbiome dysbiosis

牙龈卟啉单胞菌感染

肠道菌群失调

To elucidate the mechanism behind P. gingivalis-mediated intestinal inflammation, 16S rRNA and ITS sequencing was performed on the cecal samples of the mice that were given oral gavage of P. gingivali

NIAID Data Ecosystem50

Gut microbiome dysbiosis associated with pancreatic cancer in mice

癌症微生物组

肠道菌群失调

To analyze the effect of pancreatic cancer on mouse gut microbiome, C57BL/6 (wild-type, WT) mice were orthotopically implanted with pancreatic ductal adenocarcinoma cell line (PDAC). Microbiota analys

NIAID Data Ecosystem70

Gut microbiota in children with non-alcoholic fatty liver disease

儿童非酒精性脂肪肝病

肠道菌群失调

Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease in children worldwide. Gut microbiota and their metabolites may influence NAFLD. Therefore, this stu

NIAID Data Ecosystem60

Shotgun Metagenomics Fecal Microbiome Dysbiosis in Parkinsons Disease

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