Human CMV-specific vs IAV-specific CD8 TCM cells

We compared CD8 TCM cells specific for a CMV epitope (pp65495-503) and an influenza A virus (IAV) epitope (M158-66) of the same healthy adults and identified genes whose expression are altered in CMV-specific compared to IAV-specific TCM cells. Transcriptional profiling of CMV-specific vs IAV-specific CD8 TCM cells from healthy human. Goal was to determine the differentially expressed genes between these two antigen-specific CD8 TCM cells. CMV-specific vs IAV-specific CD8 TCM cells. Biological replicates: 2 CMV-specific replicates, 2 IAV-specific replicates.