Pressure ulcer and delayed healing: role of Proteus mirabilis and Gram-positive anaerobic cocci

The evolution of the wound is generally defined by its microbiota, although some bacteria can influence the wound's outcome by delaying healing.Bacterial interaction is expected to be a crucial factor influencing the chronicity of the wound. Proteus mirabilis has been detected as a pathogen associated with poor wound evolution, while the presence of other Gram-positive anaerobic cocci may decrease its effect on the wound. This was demonstrated in an in vitro model to study this interaction at different levels.