Crystal structure of HCV NS5B RNA polymerase in complex with novel class of dihydropyrone-containing inhibitor.
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Crystal structure of HCV NS5B RNA polymerase in complex with novel class of dihydropyrone-containing inhibitor. Descriptor: (6S)-6-CYCLOPENTYL-6-[2-(3-FLUORO-4-ISOPROPOXYPHENYL)ETHYL]-4-HYDROXY-5,6-DIHYDRO-2H-PYRAN-2-ONE, HEPATITIS C VIRUS NS5B RNA POLYMERASE Authors: Li, H, Love, R.L. Deposit date: 2006-06-12 Release date: 2006-09-05 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors. Bioorg.Med.Chem.Lett., 16, 2006
创建时间：
2006-06-12
