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Gene profiles of pathway interference downstream neurofibromin signaling

ChEBI2013-03-15 更新2026-07-21 收录

信号通路基因表达谱

神经纤维瘤病机制研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-39764 数据链接链接失效反馈

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资源简介：

Gene profiles of pathway interference downstream neurofibromin signaling

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创建时间：

2013-03-15

信号通路基因表达谱

高通量药物筛选

We conducted a proof-of-concept experiment to explore the possibility of using gene expression-based high throughput screening (GE-HTS) to find inhibitors of a signaling cascade, using platelet derive

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神经纤维瘤病机制研究

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Neurofibromatosis type 1 (NF1) is a common monogenic tumor-predisposition disorder that arises secondary to mutations in the tumor suppressor gene NF1. Haploinsufficiency of NF1 fosters a permissive t

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The Receptor Tyrosine Kinase Alk Controls Neurofibromin Functions in Drosophila Growth and Learning

神经纤维瘤病机制研究

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Anaplastic Lymphoma Kinase (Alk) is a Receptor Tyrosine Kinase (RTK) activated in several cancers, but with largely unknown physiological functions. We report two unexpected roles for the Drosophila o

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Genetic and Functional Studies Implicate Synaptic Overgrowth and Ring Gland cAMP/PKA Signaling Defects in the Drosophila melanogaster Neurofibromatosis-1 Growth Deficiency

神经纤维瘤病机制研究

果蝇遗传模型

Neurofibromatosis type 1 (NF1), a genetic disease that affects 1 in 3,000, is caused by loss of a large evolutionary conserved protein that serves as a GTPase Activating Protein (GAP) for Ras. Among D

Figshare2016-01-18 更新00

Gene profiles of pathway interference downstream neurofibromin signaling

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