Proportion of patients falling below, between, and above the Virco Clinical Cut-offs (All BC Virtual Phenotypes with one or more IAS Key mutation).

The drugs DLV and RTV were not included because the Virco clinical cut-offs are not reported for these agents.*A total of 3 drugs have only one biological cut-off (for in vitro susceptibility): FTC, NVP, and EFV.The category (below, between, above) where a majority of samples fall is bolded for each agent.AZT – zidovudine, 3TC – lamivudine; ddI – didanosine; d4T – stavudine; ABC – abacavir; FTC – emtricitabine; TDF – tenofovir; NVP – nevirapine; EFV – efavirenz; ETR – etravirine; /r – ritonavir boosted; IDV – indinavir; NFV – nelfinavir; SQV – saquinavir; FPV – fosamprenavir; LPV – lopinavir; ATV – atazanavir; TPV – tipranavir; DRV – darunavir.