Consequences of MGME1 and POLG EXO nucleases Deficiencies for mtDNA Integrity
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP471271
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资源简介：
Here we show that mtDNA has a series of abnormalities in Mgme1 knock out (Mgme1 KK) and POLG exonuclease deficient Mutator (Polg MM) mouse hearts. Next generation sequencing of mutant hearts showed abundant duplications in the D-loop region and unique 100bp duplications evenly spaced throughout the genome in Mgme1 KK hearts.
创建时间：
2024-01-06
