Table S1 - The Subthalamic Microlesion Story in Parkinson's Disease: Electrode Insertion-Related Motor Improvement with Relative Cortico-Subcortical Hypoactivation in fMRI

Individual description of the PD patient's group (N = 12). ID – patient's identification number; age – age of patient at surgery in years; G – gender: male (M); DD – duration of the PD in years; LD – duration of the levodopa treatment in years; MC – duration of motor complications in years; UPDRS-III in sessions 1–4: First number refers to OFF condition (medication OFF in session 1; medication OFF and STN DBS OFF in sessions 2 and 3), second number refers to mON condition (after administration of 250 mg of levodopa/carbidopa) in session 1 and to sON condition (medication OFF and bilateral STN DBS ON) in sessions 2, 3, 4. ND – not done in session 4; H – right (R) and left (L) hemisphere; MIE – number of microelectrodes out of 5 microelectrodes which reached the STN during the exploration phase of the surgery; Le – length (mm) of the STN measured by the microelectrode with the longest hit; Tr – microelectrode trajectory (c: central, m: medial, l: lateral, a: anterior, p: posterior) finally used for permanent electrode; MAE – number of macroelectrode trajectories used for perioperative clinical testing; SCO – subcortical oedema score; CO – cortical oedema score; coordinates od the permanent electrode (Medtronic, type 3389) contact 0 and contact 3 were measured in native space according to methodology [37] on T1-MRI obtained one year after surgery. The x-coordinate was measured from the wall of the third ventricle (+ towards right; − towards left), whereas the y-coordinate (+ towards anterior; − towards posterior) and z-coordinate (+ towards vertex; − towards brainstem) were measured from the mid-commissural point.
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