five

MLN4924 in chronic lymphocytic leukemia

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE44864
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CLL cells obtained from patients with CLL were treated with MLN4924 to determine whether NFkB transcription targets were affected by the drug. CLL cells were treated with 1 microM MLN4924 or vehicle control for 24 hours. Cells were collected by centrifugation and B-cell were purified using negative selection (B cell purification Kit, Multenyi Biotech). RNA was isolated and submitted for Gene expression analysis
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2018-08-13
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