Quantitative Analysis of p53 and/or TGFBR2 Knockdown Endothelial Transcriptomes after Irradiation. Quantitative Analysis of p53 and/or TGFBR2 Knockdown Endothelial Transcriptomes after Irradiation

Transcriptional profiling p53 or TGFBR2 knockdown HUVECs with or without irradiation. Overall design: mRNA profiles of control, p53 knockdown, TGFBR2 knockdown, and p53+TGFBR2 knockdown endothelial cells with or without irradiation were generated by deep sequencing using Illumina HiSeq 2500. HUVEC cells were collected 48 hrs post-irradiation. Two biological replicates for each condition were pooled together and sequenced.