Point mutations and InDels frequencies in the naive and selected repertoires (G0 and G17, respectively).

aThe frequencies of InDels and point mutations were subtracted from the background frequencies found in the respective repertoire, G0 or G17. The latter were determined by sequencing of a 98 nts region that was not subjected to the error-prone PCR mutagenesis, and were found to be 2.1×10−5 for G0 and 1.6×10−5 for G17. The background frequencies for point mutations were found to be 1.7×10−3 for G0 and 8.6×10−4 for G17.bThe percent values relate to the fraction of a particular InDel type out of all InDels in the respective repertoire, G0 or G17.