ADC-162 in complex with boronic acid transition state inhibitor MB076
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ADC-162 in complex with boronic acid transition state inhibitor MB076 Descriptor: 1-[(2R)-2-{2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]acetamido}-2-boronoethyl]-1H-1,2,3-triazole-4-carboxylic acid, Beta-lactamase, GLYCINE, ... Authors: Powers, R.A, Wallar, B.J, June, C.M, Fernando, M.C. Deposit date: 2023-01-06 Release date: 2023-07-05 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Synthesis of a Novel Boronic Acid Transition State Inhibitor, MB076: A Heterocyclic Triazole Effectively Inhibits Acinetobacter -Derived Cephalosporinase Variants with an Expanded-Substrate Spectrum. J.Med.Chem., 66, 2023
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2023-01-06
