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The essential genome of Plasmodium knowlesi reveals antimalarial susceptibility determinants

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1116591
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10 unique pools of P. knowlesi H strain(YH1 substrain) transfectants were generated in rhesus macaque red blood cells (RBCs) to construct a high-density mutant library, which reveals the high-resolution essential genome. Drug perturbations under GNF179 and DHA treatment were performed as well in order to find the determinants of antimalarial susceptibility .
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2024-05-25
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