Data and code from: Viscoelasticity explains fast adaptation in the auditory amplifiers of mammals

When we hear, sound-induced deflections of our sensory outer-hair-cell bundles are transduced into receptor currents. These receptor currents drive the cochlear amplifier, which is required for our ear's high sensitivity, broad dynamic range, and sharp frequency selectivity. Adaptation maintains the sensitivity of receptor currents to bundle deflections, but the mechanisms underlying adaptation in outer-hair-cell bundles remain under debate, and how adaptation works at physiologically relevant frequencies is unclear. We propose a mechanism for the fastest components of adaptation, based on viscoelastic adaptation elements. To evaluate this proposal, we fit a mathematical model of an outer-hair-cell bundle with viscoelastic adaptation elements to twelve independent experimental observations. We validate the model by successfully predicting an observation not used for fitting --- how much receptor-current sensitivity is maintained by fast adaptation. The experimentally constrained model p..., , # Data and code from: Viscoelasticity explains fast adaptation in the auditory amplifiers of mammals

Dataset DOI: [10.5061/dryad.w3r22813p](10.5061/dryad.w3r22813p)

## Description of the data and file structure

### Description of the data and file structure

The data is in CSV format and can be read by any text editor. These data are measured values for different hair bundles.

#### Files and variables

A_14pts_Peng13Fig4H.csv contains adaptation extent values.

Ppeak_Peng13Fig1a.csv contains peak current values.

Ppeak_Peng13Fig2a.csv contains peak current values.

Ppeak_Peng13Fig4a.csv contains peak current values.

Prest_Peng13FigS3C.csv contains resting current values.

R_14pts_Peng13Fig4G.csv contains long timescale fraction values.

Shift_Peng13Fig6C.csv contains adaptation shift values.

tau1_14pts_Peng13Fig4E.csv contains short timescale values.

tau2_14pts_Peng13Fig4F.csv contains long timescale values.

### Code/software

Mathematica 14 or later, or the free Wolfram Player ...,