Main input parameter values for Greater Vancouver Area (GVA) contact network model.

HI = hemagglutination inhibition assay; SPR = Sero-protection rate – defined as the proportion (%) considered sero-protected on the basis of having met or exceeded the specified antibody titre threshold.pre-H1N1pdm09: 2009 H1N1 pandemic virus; SPR based on PRE-pandemic antibody levels in 2009 or earlier.post-H1N1pdm09: 2009 H1N1 pandemic virus; SPR based on POST-pandemic antibody levels fall 2010.H3N2v: swine-origin H3N2 variant strain; SPR based on antibody levels in fall 2010.post-Brisbane: a seasonal human influenza H3N2 virus; SPR based on antibody levels fall 2010.aStatistics Canada 2006 Community Profiles [http://www12.statcan.ca/census-recensement/2006/dp-pd/prof/92-591/index.cfm?Lang=E].bThe same typical seasonal influenza parameter values were applied to each of the three influenza viruses assessed, recognizing their human influenza virus ancestral origins.cBased on 100% SPR defined at HI titre ≥40; dBased on 50%SPR defined at HI titre ≥40; e100%SPR defined at HI titre ≥80.Note that a blended composite of sero-protection based on a gradient of immunity defined as ¼SPR20, ½SPR40, ¾SPR80 and 100% SPR160 was also explored (see Table S1 and narrative).