Ivorenolide A, an Unprecedented Immunosuppressive Macrolide from Khaya ivorensis: Structural Elucidation and Bioinspired Total Synthesis
收藏Figshare2016-02-20 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Ivorenolide_A_an_Unprecedented_Immunosuppressive_Macrolide_from_Khaya_ivorensis_Structural_Elucidation_and_Bioinspired_Total_Synthesis/2457433
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Ivorenolide A (1), a novel 18-membered macrolide featuring conjugated acetylenic bonds and five chiral centers, was isolated from Khaya ivorensis. The structure of 1 was fully determined by spectroscopic analysis, single-crystal X-ray diffraction, and bioinspired total synthesis. Both compound 1 and its synthetic enantiomer 2 showed potent and selective immunosuppressive activity.
创建时间：
2016-02-20
