Buruli ulcer (BU) disease, a neglected necrotizing tropical skin infection caused by Mycobacterium ulcerans, is the third most common mycobacterial disease after tuberculosis and leprosy. Infections m
*Quantities indicate the amounts of immunogen or adjuvant delivered to each mouse in the indicated group. S = soluble protein; E = encapsulated protein. Subscripts indicate amount of soluble or encaps
aRhesus monkeys 5 animals per group.bVaccines are mixtures of vectors expressing the individual antigens PkCSP, PkAMA1, PkSSP2, and PkMSP1.cRecombinant VRP, 5×107 IU/dose each antigen.dRecombinant Ad5