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Increased Cathespin S in Blimp-1 -/- dendritic cells alters the TFH repertoire and contributes to autoimmunity. Mus musculus breed:C57BL/6

NIAID Data Ecosystem2026-03-10 收录

T细胞受体多样性

T滤泡辅助细胞

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA385859 数据链接链接失效反馈

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资源简介：

TCR beta CDR3 repertoire of TFH cells in various mutant mice.

应用场景：

创建时间：

2017-05-08

T细胞受体多样性

蝙蝠免疫基因

IntroductionBats are recognized as natural reservoirs for many viruses, and their unique immune system enables them to coexist with these viruses without frequently exhibiting disease symptoms. Howeve

NIAID Data Ecosystem50

Bovine peripheral blood T cell receptor gamma chain receptor repertoire

T细胞受体多样性

牛类免疫学

This study employs Illumina paired end 150bp sequencing technology to analyze the TCR gamma chain receptor repertoire of three bovine species. We designed specific primers targeting the bovine TCR gam

NIAID Data Ecosystem30

Human follicular helper T lymphocytes critical players in antibody responses

T滤泡辅助细胞

免疫应答机制

ABSTRACT Follicular helper T lymphocytes are a subpopulation of CD4+ T lymphocytes initially identified in germinal centers of follicles found in secondary lymphoid organs. The primary function of fol

Figshare2021-03-01 更新10

TCR repertoire sequencing from WT and Malt1PD mice

T细胞受体多样性

自身免疫疾病机制

During the development of the multi-organ inflammatory disease observed in Malt1PD mice, specific pathogenic T cell clones may expand and infiltrate affected tissues. Thus, we compared the TCR reperto

NIAID Data Ecosystem40

BCL6 orchestrates Tfh differentiation via multiple distinct mechanisms. Homo sapiens

T滤泡辅助细胞

转录因子调控

Tfh cells are required for T cell help to B cells, and BCL6 is the defining transcription factor of Tfh cells. However, the functions of Bcl6 in Tfh have largely remained unclear. Here we defined the

NIAID Data Ecosystem30

Increased Cathespin S in Blimp-1 -/- dendritic cells alters the TFH repertoire and contributes to autoimmunity. Mus musculus breed:C57BL/6

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