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Structure of human Bcl-2 in complex with THIQ-phenyl pyrazole compound

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Protein Data Bank Japan2024-05-15 更新2026-03-21 收录
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Structure of human Bcl-2 in complex with THIQ-phenyl pyrazole compound Descriptor: 1-[2-[[(3~{S})-3-(aminomethyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]carbonyl]phenyl]-~{N},~{N}-dibutyl-5-methyl-pyrazole-3-carboxamide, ACETATE ION, Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2,Bcl-2-like protein 1 Authors: Dokurno, P, Murray, J, Davidson, J, Chen, I, Davis, B, Graham, C.J, Harris, R, Jordan, A.M, Matassova, N, Pedder, C, Ray, S, Roughley, S, Smith, J, Walmsley, C, Wang, Y, Whitehead, N, Williamson, D.S, Casara, P, Le Diguarher, T, Hickman, J, Stark, J, Kotschy, A, Geneste, O, Hubbard, R.E. Deposit date: 2019-01-11 Release date: 2019-06-12 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1. Acs Omega, 4, 2019
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2019-01-11
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