Additional file 1 of African ancestry-derived APOL1 risk genotypes show proximal epigenetic associations

Additional file 1: Table S1. Characteristics of WHI African American participants used for discovery and replication of meQTL CpGs. Table S2. Significant meQTL CpGs of APOL1 risk variants in WHI-BAA23 and replication in WHI-EMPC. Table 3. CpG association findings in models including SNPs and APOL1. Table S4: eFORGE annotations for top 5 CpGs across DNase I hotspots from the Roadmap Epigenomics consortium. Table S5: eFORGE annotations for top 5 CpGs across HMM chromatin states from the Roadmap Epigenomics consortium. Table S6: eFORGE annotations for top 5 CpGs across histone mark broadPeaks from the Roadmap Epigenomics consortium. Fig. S1. Manhattan plot showing CpGs associated with APOL1 risk alleles in the discovery study. X-axis shows the chromosome positions and Y-axis the -log10(p-value) for associations. The horizontal line is the significance threshold.