Transcriptomic analysis of peripheral blood mononuclear cells (PBMC) in psoriasis patients treated with guselkumab

Psoriasis is a worldwide chronic inflammatory skin disease. The treatment is usually designed according to its severity. In this research, RNA-seq was performed on the peripheral blood mononuclear cells (PBMCs) of 12 patients with psoriasis before and after treatment (4 week) of guselkumab. Comparative gene expression profiling analysis of RNA-seq data for peripheral blood mononuclear cells (PBMCs) from 12 psoriasis patients, before and 4 weeks after treatment of gulselkumab