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Association details of lead variants from HostSeq.

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Figshare2024-03-22 更新2026-04-28 收录
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Top loci in HostSeq after applying a MAF > 5% filter and removing variants in the GIAB difficult-to-sequence regions. Chromosome 6 hit passes the genome-wide significance threshold of P 2 = 0.42). Chromosome 3 hit is also in LD with a HGI7no lead variant (rs17763742: D’ = 0.95; r2 = 0.82). Nearest-gene annotation is from myLocusZoom. Multi-ancestry meta-analysis p-values of HostSeq are added in paranthesis after primary HostSeq results (MR-MEGA); ‘m’ indicates number of ancestries MR-MEGA used for the result.
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2024-03-22
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