Rora, Ep300 bind Npas2 gene
收藏reactome.org2025-03-26 收录
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Rora binds RRE DNA elements and recruits the coactivators PGC-1alpha (Ppargc1a) and p300 (Ep300, a histone acetylase). Rora binds the promoter of the Npas2 gene and enhances transcription.
Rora与RRE DNA元件相结合,并招募共激活因子PGC-1alpha(Ppargc1a)和p300(Ep300,一种组蛋白乙酰化酶)。Rora结合Npas2基因的启动子并增强转录。
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