Crystal structure of human protein kinase CK2 alpha subunit in complex with the inhibitor CX-5279
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Crystal structure of human protein kinase CK2 alpha subunit in complex with the inhibitor CX-5279 Descriptor: 1,2-ETHANEDIOL, 3-(cyclopropylamino)-5-{[3-(trifluoromethyl)phenyl]amino}pyrimido[4,5-c]quinoline-8-carboxylic acid, Casein kinase II subunit alpha, ... Authors: Battistutta, R, Papinutto, E, Lolli, G, Pierre, F, Haddach, M, Ryckman, D.M. Deposit date: 2011-03-09 Release date: 2011-12-07 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer. Biochemistry, 50, 2011
创建时间:
2011-03-09



